2-Pyridineacetonitrile, 5-bromo-
2-(5-Bromopyridin-2-yl)acetonitrile
CAS: 312325-72-7
Molecular Formula: C7H5BrN2
2-Pyridineacetonitrile, 5-bromo- - Names and Identifiers
2-Pyridineacetonitrile, 5-bromo- - Physico-chemical Properties
| Molecular Formula | C7H5BrN2 |
| Molar Mass | 197.03 |
| Density | 1.575±0.06 g/cm3(Predicted) |
| Melting Point | 29 °C |
| Boling Point | 285.4±25.0 °C(Predicted) |
| pKa | 0.82±0.22(Predicted) |
| Storage Condition | Inert atmosphere,2-8°C |
| Sensitive | Irritant |
| MDL | MFCD07644625 |
2-Pyridineacetonitrile, 5-bromo- - Introduction
2-(5-Bromopyridin-2-yl)acetonitrile is an organic compound with the chemical formula C8H6BrN and a molecular weight of 194.05g/mol. It is a colorless to pale yellow solid with hygroscopic properties.
This compound has a wide range of applications in organic synthesis. It is an important intermediate in many organic synthesis reactions and is commonly used in the synthesis of complex organic compounds such as drugs, pesticides and dyes. It can participate in nucleophilic substitution, preparation of carboxylic acid esters and the like.
The method for preparing 2-(5-Bromopyridin-2-yl)acetonitrile is by reacting 2-bromopyridine with acetonitrile. First, 2-bromopyridine is reacted with an appropriate amount of a base such as sodium hydroxide in an organic solvent such as acetonitrile to form 2-(5-bromo-2-pyridine) ethanone. Then, the obtained 2-(5-bromo-2-pyridine) ethanone was reacted again with acetonitrile under basic conditions to obtain the final product 2-(5-Bromopyridin-2-yl)acetonitrile.
Regarding safety information, 2-(5-Bromopyridin-2-yl)acetonitrile may be harmful and irritating. Contact with skin and eyes may cause irritation and redness. Gloves, protective glasses and external laboratory goggles should be worn during handling to avoid direct contact. In addition, it should be used in a well-ventilated place to avoid inhaling its gas. If ingested or inhaled, medical assistance should be sought immediately. For detailed safety information, please refer to the relevant Chemical Safety Data Sheet (SDS) or consult a professional.
This compound has a wide range of applications in organic synthesis. It is an important intermediate in many organic synthesis reactions and is commonly used in the synthesis of complex organic compounds such as drugs, pesticides and dyes. It can participate in nucleophilic substitution, preparation of carboxylic acid esters and the like.
The method for preparing 2-(5-Bromopyridin-2-yl)acetonitrile is by reacting 2-bromopyridine with acetonitrile. First, 2-bromopyridine is reacted with an appropriate amount of a base such as sodium hydroxide in an organic solvent such as acetonitrile to form 2-(5-bromo-2-pyridine) ethanone. Then, the obtained 2-(5-bromo-2-pyridine) ethanone was reacted again with acetonitrile under basic conditions to obtain the final product 2-(5-Bromopyridin-2-yl)acetonitrile.
Regarding safety information, 2-(5-Bromopyridin-2-yl)acetonitrile may be harmful and irritating. Contact with skin and eyes may cause irritation and redness. Gloves, protective glasses and external laboratory goggles should be worn during handling to avoid direct contact. In addition, it should be used in a well-ventilated place to avoid inhaling its gas. If ingested or inhaled, medical assistance should be sought immediately. For detailed safety information, please refer to the relevant Chemical Safety Data Sheet (SDS) or consult a professional.
Last Update：2024-04-09 21:01:54
